Welcome to the Vertex Investigator-Initiated Studies (IIS) Program!

Our Goal

To support independent, investigator-initiated research designed to advance scientific knowledge of disease states, patient populations, and medical treatment, in alignment with Vertex's clinical and nonclinical areas of interest

Types of Research Eligible for Support

Funding and/or drug support may be available for the following categories of research:

• Clinical studies involving INCIVEK™ (telaprevir) and ivacaftor*
• Observational studies that support research into hepatitis C and cystic fibrosis disease states, e.g., epidemiological and outcomes studies
• Nonclinical studies using Vertex products for in vitro assays or in vivo models

* Ivacaftor clinical studies may not be initiated until after ivacaftor regulatory approval in the country where the study is to take place.

Research Programs of Interest

• Hepatitis C
• Cystic fibrosis
• Infectious disease*
• Oncology*
• Inflammation and immune-mediated disease*
• CNS disease, including pain*

*Nonclinical research only

Proposal Submission Process

Applicants to the Vertex IIS Program must initially submit a brief concept proposal that summarizes the proposed research and support requested. If a clinical concept proposal is accepted, a detailed study protocol and budget must then be submitted for final approval. Nonclinical concept proposals typically require a single submission and a detailed protocol is rarely needed.

For more information, download our Investigator-Initiated Program Overview.

Please be advised that details of the research proposal are often shared with multiple functions within the company in order to facilitate appropriate internal review. While no information will be shared externally, we cannot guarantee confidentiality will be maintained in regard to any information submitted for review.

Submission of a proposal does not guarantee eventual funding or drug support. Vertex's support of an Investigator-Initiated Study in no way implies any obligation regarding recommendation or prescribing of products, now or in the future.

Please note: It is possible your SPAM filter will remove Vertex IIS emails from your inbox. You must add the Vertex IIS email address (vrtx_iisgrants@vrtx.com) and technical client services email address (vertex@steeprockinc.com) to your address book to prevent these e-mails from entering your SPAM folder.